Statistics 597D
Topics in Statistical Genetics and Bioinformatics
Spring 2001

General Information

General Information - Lecture Notes - Assignments

Course Announcements and working group assignments
Final project assignment (postscript version)
GroupChosen ProjectPresentation day
1Project DThursday
2Project ETuesday
3Project FTuesday
5Project CThursday
6Project DThursday
7Expressed Sequence TagsTuesday

Time and Place Tuesdays and Thursdays 2:30-3:45, 201 Thomas
Instructors Francesca Chiaromonte
411 Thomas

Dave Hunter
310 Thomas
Textbook There is no textbook for this course. However, many of Dave's lectures will be based on material found in Mathematical and Statistical Models for Genetic Analysis by Kenneth Lange (Springer, 1997). I placed the book on reserve. However, what I didn't know is that is takes a while to show up on reserve (sorry I didn't do it soon enough so that it would be available at the start of the class). If you want to purchase the book, you can do it online at quite easily. You can also purchase it directly from Springer (click on the title of the book above).
In addition, if you're new to the subject of genetics and just want a basic introductory text on population genetics, there are a lot of such books available (just check the library). Let me recommend one, Principles of Population Genetics, 3rd edition by Daniel Hartl and Andrew Clark, (1997, Sinauer Associates). This is the same Andrew Clark who teaches at Penn State!
Computing (Splus) Numerical work will play a large role in the homework assignments (see the online syllabus). If you don't have a particular preference and want to learn a bit about Splus, there is some documentation on the web. A concise Guide to Splus by Brian Ripley is available online in postscript form, as is a more complete set of Splus Notes written by Bill Venables and Dave Smith. Finally, some documentation on Splus is available on MathSoft's website. I recommend starting with the Ripley guide, particularly sections 4, 6, 8, 11, and 12. There is a free Splus clone called R that can be downloaded at
More information Consult the syllabus or contact one of the instructors. In addition, here is the pdf version of the notes Francesca used during the first lecture.

Last updated: April 10, 2001